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 This Product Bulletin will discuss the dangers of hypoglycemia in diabetes patients residing in a long-term care environment. It will then discuss the possible advantages of incorporating Levemir into the treatment regimen of this patient group. 
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Issue
- Issue Number:1 Jan 09 Supplement
Click here for Part II of III
Release date: January 15, 2009
Expiration date: January 14, 2011
Estimated time to complete: 1.75 hoursThe Management of Diabetic Neuropathy and Glycemic Control in Long-Term Care Facilities
A Multisupported CME MonographRichard Bedlack, MD, PhD
Activity Medical Director
Associate Professor of Neurology
Duke University School of Medicine
Durham, NCStephen M. Caiola, MS
Activity Reviewer
Ass - Issue Number:1 Jan 09 Supplement
Click here for Part III of III
Introduction
The prevalence of diabetes mellitus is estimated at 180 million, and the World Health Organization projects that prevalence will double from that level by the year 2030.1 Approximately half of the patients with diabetes mellitus will develop a preventable but devastating complication called diabetic peripheral neuropathy (DPN).2
This educational activity recaps the epidemiology, classification, diagnosis, and pathology of diabetic neuropathy and sum
- Issue Number:1 Jan 09 Supplement
Pathophysiology
How Does Diabetes Mellitus Cause Nerve Damage?
Although the pathophysiology of diabetic neuropathy is unclear, most experts believe that hyperglycemia is the cause of the nerve damage in DPN.48 Hyperglycemia causes increased levels of intracellular glucose in nerves, leading to saturation of the normal glycolytic pathway.49 Nevertheless, different neuropathies may have different (and perhaps overlapping) mechanisms; for example, with focal or asymmetrical diabetic neuropathy syndromes, vascular injury or autoimmunity may play more important roles
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Anytown, Alabama
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Thomas T. Yoshikawa, MD
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