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Diabetes Management: The Hidden Challenge of Managing Hyperglycemia in Long-Term Care Settings

  • Fri, 9/5/08 - 4:54pm
  • 0 Comments
  • 5495 reads
Author(s): 

Barbara Resnick, PhD, CRNP, FAAN, FAANP

Diabetes affects approximately 20% of nursing home residents.1 The impact of diabetes is devastating in these individuals, with 90% of nursing home residents with diabetes having evidence of coronary artery disease, stroke, and/or peripheral vascular disease. These individuals tend to have 6.4 major diagnoses, compared with only 2.4 in residents without diabetes. Much of the research in this area has focused on describing diabetic care behaviors of providers in nursing homes, and conclusions generally indicated that this care has been inadequate.2-5 Guidelines have been developed based on best practices for management of diabetes with older adults;6,7 however, these guidelines are not well disseminated or utilized.8 For residents in long-term care facilities, subsequent micro- and macrovascular disease may not be important to them. Rather, it is the day-to-day impact of diabetes management on functional activities, mood, cognition, and quality of life that is relevant. It is therefore particularly important to consider the daily impact of diabetes on these individuals, as well as the more commonly ignored and neglected problem of hyperglycemia.

IMPACT OF DIABETES

Diabetes can result in serious morbidity and mortality from micro- and macrovascular complications.9 Complications include heart attack, stroke, diabetic retinopathy, end-stage renal failure, peripheral vascular disease, peripheral neuropathy, cognitive impairment, sexual dysfunction, and multiple gastrointestinal, urological, and cardiovascular symptoms.10-12 Repeatedly it has been shown that glucose control can prevent or slow the progression of these devastating microvascular complications of diabetes.13 Specifically, there is a 25-30% reduction in the development of the microvascular complications for every 1% reduction in glycosylated hemoglobin (HbA1c). Unfortunately, 8 years of treatment are needed before the benefits of glycemic control are appreciated.14 Likewise, it takes time (approximately 2-3 years) to reap the benefits of blood pressure and lipid management in type 2 diabetes with regard to microvascular problems.14,15 Glucose control has not been proven to be a significant factor for the prevention of macrovascular disease.14 Hyperglycemia is noted, however, to have significant short-term effects on older adults causing slowed brain function, lethargy, and dehydration.16 Generally, in the long-term care setting, treatment goals are to restore the metabolic abnormalities to as nearly normal as possible, and to adequately control blood pressure and lipids.6,7 The ultimate purpose of the recommended goals is to reduce morbidity, mortality, and patient care costs in individuals with diabetes.

RECOGNITION OF DIABETES AND HYPERGLYCEMIA

The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus developed guidelines for the diagnosis of diabetes (Table I).17 These guidelines maintain that a diagnosis of diabetes should be entertained when there is a fasting glucose of greater than 125 mg/dL and an oral glucose tolerance test (2-hour) that results in a glucose level of greater than 199 mg/dL.

There are many factors that influence the development of hyperglycemia and diabetes in older adults, as shown in the Figure.18 Insulin resistance is particularly common in older individuals; however, insulin secretion can likewise be a problem. Impaired beta-cell compensation to age-related insulin resistance may particularly predispose older individuals to develop hyperglycemia and type 2 diabetes.

Traditional signs and symptoms of hyperglycemia are often different in older adults when compared to younger individuals.

References: 

References 1. Mayfield JA, Deb P, Potter DEB. Diabetes and long-term care. In: Harris MI, ed. Diabetes in America. 2nd ed. Bethesda, MD: National Institutes of Health (Publication No. 95-1468); 1995: 571-686. 2. Benbow SJ, Walsh A, Gill GV. Diabetes in the institutionalized elderly: A forgotten population? BMJ 1997;315:1868-1870. 3. Molyneux D. Chronic disease in institutionalized patients: Care is worse for several chronic diseases in institutionalized patients. BMJ 1997;315:1539-1540. 4. Berry RM, Raleigh ED. Diabetic foot care in a long-term facility. J Gerontol Nurs 2004;30(4):8-13. 5. Reed R, Mooradian AD. Management of diabetes mellitus in the nursing home. Annals of Long Term Care: Clinical Care and Aging 1998;6(2):102-108. 6. California Healthcare Foundation/American Geriatrics Society Panel in Improving Care for Elders with Diabetes. Guidelines for improving the care of older person with Diabetes mellitus. J Am Geriatr Soc 2003;51: S265-S280. 7. American Medical Directors Association. Managing Diabetes in the Long-Term Care Setting, Clinical Practice Guideline. Columbia, MD: American Medical Directors Association; 2002. 8. Simonson W. The Senior Care Source: An Interdisciplinary Survey of Long-Term Care Health Professionals. Albuquerque, NM: Wellman Publishing, Inc.; 2004. 9. Tedesco JV, Wright RS, Williams BA, et al; Mayo Coronary Care Unit Group. Effect of diabetes on the mortality risk of cardiogenic shock in a community-based population. Mayo Clin Proc 2003;78 (5):561-566. 10. Gregg EW, Yaffe K, Cauley JA, et al. Is diabetes associated with cognitive impairment and cognitive decline among older women? Study of Osteoporotic Fractures Research Group. Arch Intern Med 2000;160(2):174-180. 11. Grodstein F, Chen J, Wilson RS, Manson JE. Nurses’ Health Study: Type 2 diabetes and cognitive function in community-dwelling elderly women. Diabetes Care 2001;24(6):1060-1065. 12. Schwartz AV, Hillier TA, Sellmeyer DE, et al. Older women with diabetes have a higher risk of falls: A prospective study. Diabetes Care 2002; 25(10):1749-1754. 13. Orchard TJ. From diagnosis and classification to complications and therapy. DCCT, Part II: Diabetes Control and Complications Trial. Diabetes Care 1994;17(4):326-338. 14. United Kingdom Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes. BMJ 1998;7:703-713. 15. Grover S, Coupal L, Zowall H, Dorais M. Cost-effectiveness of treating hyperlipidemia in the presence of diabetes: Who should be treated? Circulation 2000;102(7):722-727. 16. Cox DJ, Kovatchev BP, Gonder-Frederick LA, et al. Relationships between hyperglycemia and cognitive performance among adults with type 1 and type 2 diabetes. Diabetes Care 2005;28(1):71-77. 17. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 1997;20:1183-1197. 18. Chang A, Halter J. Aging and insulin secretion. Am J Physiol Endocrinol Metab 2003;284(1):E7-E12. 19. Vinik AI, Vinik E. Prevention of the complications of diabetes. Am J Manag Care 2003;9(3 Suppl):S63-S80. 20. American Diabetes Association. Implications of the Diabetes Control and Complications Trial. Diabetes Care 2003;26(Suppl 1):S25-S27. 21. Haffner SM; American Diabetes Association. Management of dyslipidemia in adults with diabetes. Diabetes Care 2003;26(Suppl 1):S83-S86. 22. American Diabetes Association. Position statement: Nutrition recommendations and principles for people with diabetes mellitus. Diabetes Care 2000;23(Suppl 1):S43-S46. 23. Nied RJ, Franklin B. Promoting and prescribing exercise for the elderly. Am Fam Physician 2002; 65(3):419-426. 24. Wei M, Gibbons LW, Kampert JB, et al. Low cardiorespiratory fitness and physical inactivity as predictors of mortality in men with type 2 diabetes. Ann Intern Med 2000;132:605-611. 25. Riddle M. Timely initiation of basal insulin. Am J Med 2004;116(Suppl 3A):3S-9S. 26. Wright A, Burden AC, Paisey RB, et al; UK Prospective Diabetes Study Group. Sulfonylurea inadequacy: Efficacy of addition of insulin over 6 years in patients with type 2 diabetes in the UK Prospective Diabetes Study (UKPDS 57). Diabetes Care 2002;25(2):330-336. 27. Walter LC, Covinsky KE. Cancer screening in elderly patients: A framework for individualized decision making. JAMA 2001;285(21):2750-2756. 28. Duckworth W, Marcelli M, Padden M, et al. Improvements in glycemic control in type 2 diabetes patients switched from sulfonylurea coadministered with metformin to glyburide-metformin tablets. J Manag Care Pharm 2003;9(3):256-262. 29. Resnick B. Health promotion. In: Bernard M, Flaherty E, Ham R, Sloane P, Warshaw G, eds. Primary Care Geriatrics. 5th ed. In press. 30. Schultz J. Diabetes Management in the Nursing Home Setting: Clinical Tips. Available at: http: //www.health.state.mn.us/divs/fpc/cww/cww7_04.html. Accessed April 12, 2005. 31. Khan AJ, Cutter SM, Schulz B, et al. Nosocomial transmission of hepatitis B virus infection among residents with diabetes in a skilled nursing facility. Infect Control Hosp Epidemiol 2002;23(6):313-318.

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